A brief introduction to my research journey and scientific philosophy.
Principal Investigator · Human Genetics
I am a human geneticist and translational researcher with over a decade of experience bridging genomic discovery with clinical application. My work sits at the intersection of cardiogenetics, infectious disease genomics, and bioinformatics — leveraging large-scale multi-omic datasets to uncover disease mechanisms and identify novel therapeutic targets.
Currently leading a multidisciplinary research group at the Institute for Precision Medicine, I am committed to advancing equity in genomic medicine and building computational infrastructure for collaborative science.
Publications
Citations
Collaborations
Active Projects
"Our goal is to translate genomic complexity into clinical clarity — ensuring that every patient benefits from the precision medicine revolution."
My research spans multiple disciplines, unified by a commitment to genomic science and translational impact.
Investigating the genetic architecture of complex diseases through GWAS, whole-genome sequencing, and functional genomics approaches in diverse populations.
Developing biomarker-driven strategies and pharmacogenomic frameworks to accelerate the journey from laboratory discovery to clinical application.
Elucidating the genetic determinants of cardiovascular disease, including cardiomyopathies, arrhythmias, and lipid disorders, to enable precision cardiology.
Applying genomic epidemiology and host-pathogen interaction studies to understand transmission dynamics and inform public health responses.
Building scalable computational pipelines and machine learning models for multi-omic data integration, variant interpretation, and knowledge discovery.
My work has been published in Nature Genetics, Cell, and The New England Journal of Medicine, with over 12,000 citations and an H-index of 48. I serve on the editorial boards of three international journals and regularly advise funding agencies on genomic research strategy.
Peer-reviewed publications in leading scientific journals.
A large-scale meta-analysis across diverse populations revealing 47 novel genetic loci associated with coronary artery disease, highlighting new therapeutic targets and population-specific risk factors.
Comprehensive single-cell RNA sequencing of over 500,000 cells from healthy and failing human hearts, identifying novel cell-state transitions and intercellular communication networks in cardiomyopathy.
Real-time genomic surveillance of 85,000 viral genomes tracking the emergence, transmission, and immune escape of SARS-CoV-2 variants of concern across global populations.
An open-source computational framework for harmonizing and analyzing genomics, transcriptomics, proteomics, and metabolomics data at petabyte scale with built-in reproducibility.
A methodological framework for developing and validating polygenic risk scores that perform equitably across global populations, addressing a critical barrier to clinical implementation.
Exome-wide rare variant association study in a large biobank cohort, identifying 12 novel genes with significant burden of protein-truncating variants in dilated cardiomyopathy patients.
Visualizing key research metrics and computational genomics data.
Publications per year · 2015–2025
Sequencing depth across research projects
Impact indicators across research areas
Chromosome-level variant density · Chromosome 21
My journey through education, research positions, and scientific milestones.
University of Cambridge · Institute for Medical Research
Dissertation: "Genetic architecture of complex cardiovascular traits in multi-ethnic populations"
University of Oxford · Wellcome Centre for Human Genetics
Distinction · Thesis on statistical methods for GWAS imputation
Imperial College London · Department of Life Sciences
First Class Honours · University Prize for Outstanding Academic Achievement
Institute for Precision Medicine · Berlin, Germany
Leading a group of 12 researchers focused on human genetics and translational genomics
Broad Institute of MIT and Harvard · Cambridge, MA
Cardiovascular Disease Initiative · Stanley Center for Psychiatric Research
Wellcome Sanger Institute · Hinxton, UK
Human Genetics Programme · International Genome Sample Resource
European Research Council Consolidator Grant
Published in Cell · Single-cell heart atlas
Founded International Cardiogenetics Consortium
NIH Director's Early Independence Award
Collaborating with leading institutions worldwide to advance genomic science and translational medicine.
Institute for
Precision Medicine
Broad Institute
MIT & Harvard
Wellcome
Sanger Institute
University of
Cambridge
Max Planck
Institute
WHO
Genomics Program
I am always open to discussing new research collaborations, speaking engagements, or opportunities to advance genomic medicine.
Location
Institute for Precision Medicine
Berlin, Germany
Office
+49 30 1234 5678